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TAPI-0
TAPI-0 from MedChemExpress
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Citations:
(4)
Supplier Page
Supplier Page from
MedChemExpress for
TAPI-0
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Description
TAPI-0 is a
TACE (TNF-α converting enzyme; ADAM17)
inhibitor with an
IC
50
of 100 nM. TAPI-0 is a
MMP
inhibitor and also attenuates TNF-α processing
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
TAPI-0
Company
MedChemExpress
Price
$270.00
Supplier Page
View Company Product Page
Catalog Number
HY-118694
Quantity
1 mg
Applications
Bioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Type
Chemical
Molecular Weight
456.53
Formula
C₂₄H₃₂N₄O₅
Research Area
Infection; Cancer
Purity
98.98%
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MedChemExpress
1 Deer Park Drive, Suite F
MONMOUTH JUNCTION
,
NJ
08852
United States
Phone
: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910
Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com
Company Profile
Website:
medchemexpress.com
Citations (4)
(1)
miR-26a-5p/ADAM17-Mediated Proteolysis of TREM2 Regulates Neuroinflammation in Hypertensive Mice Following Lead Exposure
Toxics
January 5, 2025
Yuran Wang, Zeming Wang, Han Hao, Yuwei Zhao, Jian Wang, Weixuan Wang
GI (Cayman, Ann Arbor, MI, USA, 28284) to
inhibit
ADAM10
or
TAPI-0
(
MCE
, Monmouth Junction, NJ, USA,
HY-118694
) to
inhibit
ADAM17 for 2 h then treated with 10μM PbAC and 100 nM AngII for 24 h. 2.4.
Quantitative Real-Time PCR
(2)
TACE antagonists blocking ACE2 shedding caused by the spike protein of SARS-CoV are candidate antiviral compounds
Antiviral research
March 1, 2010
Haga S, Nagata N, Okamura T, Yamamoto N, Sata T, Yamamoto N, Sasazuki T, Ishizaka Y.
(3)
Metalloprotease inhibitors GM6001 and TAPI-0 inhibit the obligate intracellular human pathogen Chlamydia trachomatis by targeting peptide deformylase of the bacterium
The Journal of biological chemistry
June 16, 2006
Balakrishnan A, Patel B, Sieber SA, Chen D, Pachikara N, Zhong G, Cravatt BF, Fan H.
(4)
Tilde substitution law in thermo field dynamics: Thermal state conditions
Physical review. D, Particles and fields
January 15, 1985
Matsumoto H, Nakano Y, Umezawa H.
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TAPI-0 from MedChemExpress
Supplier Page
View Company Product Page
$270.00
Product Specs
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