Calpeptin from MedChemExpress

Product Specs
ItemCalpeptin
CompanyMedChemExpress
Price $73.00Supplier Page View Company Product Page
Catalog NumberHY-100223
Research AreaInflammation/Immunology
FormulaC₂₀H₃₀N₂O₄
Molecular Weight362.46
TypeChemical
Purity99.17%
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Quantity10 mM * 1 mL

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(1) MMP8 exacerbates sepsis-induced pulmonary vascular leakage by disruption of endothelial VE-cadherin through ERK signallingMol BiomedJuly 24, 2026Yaojun Peng, Qiyan Wu, Yuyu Liu, Di Jing, Yang Bai, Haiyan Zhu5, dissolved in DMSO; MCE, #HY-101494), a calpain inhibitor (Calpeptin; 10, dissolved in DMSO; MCE, #HY-100223), and a dynamin inhibitor (Dynasore; 20 μΜ, dissolved in DMSO; MCE, #HY-15304) for 1 h followed by septic

(2) Inhibition of calpain-mediated HMGB1 alleviates cardiac inflammation and dysfunction induced by ultra-processed foodsJCI InsightJune 8, 2026Claire Ross, Sanskruti Ravindra Gare, Nasser H.O. Alatawi, Oveena Fonseka, Xinyi Chen, Jiayan Zhang, Yihua Han, Andrea Ruiz-Velasco, Riham R.E. Abouleisa, Yingjuan Liu, et al.control mice. Drug administration. The pharmacological calpain inhibitor calpeptin (MedChemExpress, HY-100223), was administered to mice intravenously at a dose of 10 mg/kg weekly for 8 weeks (35). In addition,

(3) Detection of Calpain-Mediated Beclin-1 Cleavage for Drug Discovery in Inflammatory Bowel DiseasesCellsMay 18, 2026Kylee A. Hunter, Anne-Marie C. Overstreet, Bryon Benjamin Koff, Hridai Dharan, Steven Overend, Jeannette S. Messer(MedChemExpress, HY-13259), Dazcapistat (MedChemExpress, HY-132850), and Calpeptin (MedChemExpress, HY-100223) were diluted in reaction buffer and mixed with BICR (final concentration 0.5 μM), then porcine Calpain-1

(4) TRPC6-Calpain-1 Axis Promotes Tubulointerstitial Inflammation by Inhibiting Mitophagy in Diabetic Kidney DiseaseKidney international reportsNovember 1, 2024Liu CC, Ji JL, Wang Z, Zhang XJ, Ding L, Zhang Y, Zhou Y, Zhang DJ, Tang ZL, Cao JY, et al.glucose + 10 μM BAPTA, HY-100168, MCE), and the HG + calpeptin group (35 mM glucose + 1 μM calpeptin, HY-100223, MCE). The HG + DMSO groups (35 mM glucose + equal volume of DMSO, ST038, Beyotime, China) were used

(5) Influenza A virus inhibits TET2 expression by endoribonuclease PA-X to attenuate type I interferon signaling and promote viral replicationPLoS pathogensJuly 1, 2023Hu Y, Chen X, Ling Y, Zhou K, Han M, Wang X, Yue M, Li Y.distilled water. Protein degradation inhibitors MG132 (HY-13259), Z-VAD-FMK (HY-16658B), and Calpeptin (HY-100223) were obtained from MCE (Monmouth Junction, NJ, USA), dissolved in dimethyl sulfoxide (DMSO) (Sigma,

(6) Design of small molecule ketoamide-based inhibitors of cathepsin KBioorganic & medicinal chemistry lettersFebruary 9, 2004Catalano JG, Deaton DN, Long ST, McFadyen RB, Miller LR, Payne JA, Wells-Knecht KJ, Wright LL.

(7) Synthesis of a new cell penetrating calpain inhibitor (calpeptin)Biochemical and biophysical research communicationsJune 30, 1988Tsujinaka T, Kajiwara Y, Kambayashi J, Sakon M, Higuchi N, Tanaka T, Mori T.

(8) Bleomycin treatment for cystic hygroma in childrenNihon geka hokan. Archiv fur japanische ChirurgieSeptember 1, 1977Yura J, Hashimoto T, Tsuruga N, Shibata K.

(9) The calpain inhibitor calpeptin prevents bleomycin-induced pulmonary fibrosis in miceClinical and experimental immunologyJanuary 1, 0001"Tabata C, Tabata R, Nakano T."

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Calpeptin from MedChemExpress

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Calpeptin from MedChemExpress

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