Azosemide from MedChemExpress | Biocompare.com

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Azosemide

Description

Azosemide, a sulfonamide loop diuretic, is a potent NKCC1 inhibitor with IC₅₀s of 0.246 µM and 0.197 µM for hNKCC1A and NKCC1B, respectively

Product Specs
ItemAzosemide
CompanyMedChemExpress
Price $34.00Supplier Page View Company Product Page
Catalog NumberHY-107321
Quantity10 mM * 1 mL
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.85%
TypeChemical
Molecular Weight370.84
FormulaC₁₂H₁₁ClN₆O₂S₂
Research AreaMetabolic Disease

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(1) Azosemide is more potent than bumetanide and various other loop diuretics to inhibit the sodium-potassium-chloride-cotransporter human variants hNKCC1A and hNKCC1BScientific reportsJune 29, 2018Hampel P, Römermann K, MacAulay N, Löscher W.

(2) Pharmacokinetics and pharmacodynamics of intravenous azosemide in mutant Nagase analbuminemic ratsDrug metabolism and disposition: the biological fate of chemicalsFebruary 1, 2003Kim EJ, Lee AK, Kim SH, Kim SG, Lee MG.

(3) Trial of a long-acting antihistamine in the treatment of coryzaThe British journal of clinical practiceJanuary 1, 1976McGuinness BW.

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