Nodinitib-1 from MedChemExpress

Product Specs
ItemNodinitib-1
CompanyMedChemExpress
Price $73.00Supplier Page View Company Product Page
Catalog NumberHY-18639
Quantity10 mM * 1 mL
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.94%
TypeChemical
Molecular Weight287.34
FormulaC₁₄H₁₃N₃O₂S
Research AreaInflammation/Immunology

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(1) Peroxiredoxin 1 mediates bleomycin-induced acute lung injury in mice via macrophage NOD1/NF-κB axisRespiratory ResearchJanuary 30, 2026Guoliang Jiang, Yan Zhang, Lingzhi Long, Xiangyu Zhang, Tingting Yao, Xiaoyun Cheng, Pan Yu, Lijun Zou, Yijun He, Mao Jiang, et al.was obtained from Abnova. NF-κB inhibitor (BAY 11-7082, #HY-13453) and NOD1 inhibitor (Nodinitib-1, #HY-18639) were obtained from Medchemexpress. HiPure Total RNA Plus Kit (#R411103) was obtained from Magen Biotech.

(2) Shenqi compound enhances pancreatic β-cell secretion by promoting the maturation and transport of insulin secretory vesicles through the NOD1/RIP2 signaling pathwayFrontiers in NutritionJanuary 26, 2026Nairong Yao, Yiqian Xing, Ruobing Tang, Chunguang Xie, Qiyue Yang, Ya Liu, Xiyu Zhang6-well plates, pretreated with serum with or without ML130 (2μM, NOD1 inhibitor, MedChemExpress, USA, HY-18639) for 1 h, and then treated with 5.5 or 50 mM glucose for 24 h, followed by 15% SQC for another 24 h

(3) Activation of NOD1 on tumor-associated macrophages augments CD8(+) T cell-mediated antitumor immunity in hepatocellular carcinomaScience advancesOctober 4, 2024Zhang F, Jiang Q, Cai J, Meng F, Tang W, Liu Z, Lin X, Liu W, Zhou Y, Shen X, et al.day, InvivoGen, #tlrl-c12dap) (16, 75), ML130 (50 μg per injection, every other day, MedChemExpress, #HY-18639) (76), and anti–PD-1 antibody (200 μg per injection, every third day, Bio X Cell, #BE0146) (77) after

(4) Microbiota enterotoxigenic Bacteroides fragilis-secreted BFT-1 promotes breast cancer cell stemness and chemoresistance through its functional receptor NOD1Protein & CellMay 28, 2024Wei Ma, Lu Zhang, Weilong Chen, Zhaoxia Chang, Juchuanli Tu, Yuanyuan Qin, Yuwen Yao, Mengxue Dong, Jiajun Ding, Siqin Li, et al.of treatment were indicated in the corresponding legends. The commercial NOD1 inhibitor Nodinitib-1 (HY-18639, MedChemExpress) was used at 5–10 μmol/L for 48–72 h in vitro and 20 mg/kg in vivo. Metronidazole (MNZ)

(5) Aldehyde dehydrogenase 2-mediated aldehyde metabolism promotes tumor immune evasion by regulating the NOD/VISTA axisJournal for immunotherapy of cancerDecember 7, 2023Chen Y, Sun J, Liu J, Wei Y, Wang X, Fang H, Du H, Huang J, Li Q, Ren G, et al.4-Hydroxynonenal (4-HNE, HY-113466, MCE; 100 nM), Alda1 (S5800, Selleck; 20 µM), Nodinitib-1 (ML130, HY-18639, MCE; 10 µM) and QNZ (S4902, Selleck; 10 µM). Cells were washed with flow cytometry buffer after staining

(6) Fusobacterium nucleatum-triggered neutrophil extracellular traps facilitate colorectal carcinoma progressionJournal of experimental & clinical cancer research : CRSeptember 9, 2023Kong X, Zhang Y, Xiang L, You Y, Duan Y, Zhao Y, Li S, Wu R, Zhang J, Zhou L, et al.ROS inhibitor DPI (10 μmol/L, S8639, Selleck, Houston, Texas, USA), NOD1 inhibitor ML130 (20 ug/mL, HY-18639, MedChemExpress, New Jersey, USA), NOD2 inhibitor GSK717 (20 ug/mL, HY136555, MedChemExpress, New Jersey,

(7) Synthesis and physicochemical characterization of novel phenotypic probes targeting the nuclear factor-kappa B signaling pathwayBeilstein journal of organic chemistryJanuary 1, 2013Hershberger PM, Peddibhotla S, Sessions EH, Divlianska DB, Correa RG, Pinkerton AB, Reed JC, Roth GP.

(8) Discovery and characterization of 2-aminobenzimidazole derivatives as selective NOD1 inhibitorsChemistry & biologyJuly 29, 2011Correa RG, Khan PM, Askari N, Zhai D, Gerlic M, Brown B, Magnuson G, Spreafico R, Albani S, Sergienko E, et al.

(9) [Necrotizing ulcerative stomatitis and long term administration of steroid hormone: a report of an autopsy case]Nihon Koku Geka Gakkai zasshiJanuary 1, 1976Teshima T, Ohmura T, Sasaki M, Watanabe M, Maeda H.

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Nodinitib-1 from MedChemExpress

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