Purmorphamine from MedChemExpress

Product Specs
ItemPurmorphamine
CompanyMedChemExpress
Price $113.00Supplier Page View Company Product Page
Catalog NumberHY-15108
Quantity10 mM * 1 mL
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.9%
TypeChemical
Molecular Weight520.62
Molecule NamePurmorphamine
FormulaC31H32N6O2
Research AreaNeurological Disease; Cancer

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(1) Zinc‐Mediated Lysosomal Destabilization Links Mitochondrial Damage to Neuronal Death in a Cellular MPP + Model of Parkinson's DiseaseJ NeurochemFebruary 1, 2026Hyun-Seung Lee, Sun-Ah Kang, Jae-Won Eom, Min Seong Kim, Ji-Soo Kim, Yang-Hee KimBiosystems, Cat. No. SH7‐H5229), 2 μM purmorphamine (MedChemExpress, Monmouth Junction, NJ, USA; Cat. No. HY‐15108), and 100 ng/mL FGF8 (ACRO Biosystems, Cat. No. FGB‐H5115) were added, and 3 μM CHIR99021 (Tocris Bioscience,

(2) Apelin signaling acts as a molecular switch between endothelial and hematopoietic stem cell fatesEMBO ReportsDecember 16, 2025Jean Eberlein, Nadja Groos, Navina Shrestha Duwal, Wade W Sugden, Trista E North, Christian S M Helkerreagents" RO4929097,MedChemExpress,HY- 11102 DMH-1,Calbiochem,203646 LiCl,Sigma-Aldrich,L7026 Purmorphamine,MedChemExpress,HY -15108 Software,Software,Software GraphPad Prism 10,GraphPad Software, Imaris 9.7.2,Oxford Instruments, Fiji

(3) Rapid and Simplified Induction of Spinal Motor Neurons From Human Induced Pluripotent Stem CellsBIO-PROTOCOLOctober 20, 2025YaoYao Chen, Fan Yang, Timothy O'Brien, Sanbing Shen, Meimei YangRetinoic acid (MedChemExpress, catalog number: HY-14649) 20. Purmorphamine (MedChemExpress, catalog number: HY-15108) 21. Compound E (MedChemExpress, catalog number: HY-14176) 22. BDNF (PeproTech, catalog number: 450-02) 23.

(4) SIRT3‐Mediated Deacetylation of DRP1K711 Prevents Mitochondrial Dysfunction in Parkinson's DiseaseAdvanced ScienceFebruary 20, 2025Ye Xi, Kai Tao, Xiaomin Wen, Dayun Feng, Zifan Mai, Hui Ding, Honghui Mao, Mingming Wang, Qian Yang, Jie Xiang, et al.No. 100–45), 100 ng mL−1 FGF8 (MCE, Catalog No. HY‐P70533) and 2 µm Purmorphamine (MCE, Catalog No. HY‐15108). After five days, the culture medium was gradually switched to N2 medium supplemented with CHIR99021(Tocris,

(5) Polyethyleneimine facilitates the growth and electrophysiological characterization of iPSC-derived motor neuronsScientific ReportsOctober 30, 2024Meimei Yang, Daofeng You, Gang Liu, Yin Lu, Guangming Yang, Timothy O’Brien, David C. Henshall, Orla Hardiman, Li Cai, Min Liu, et al.in NIM containing 1 μM CHIR, 2 μM SB, 2 μM DMH1, 0.1 μM RA (HY-14649, MCE) and 0.5 μM Purmorphamine (HY-15108, MCE) for the following 6 days, with the medium changed every two days. On day 12 of differentiation,

(6) A tumorigenicity evaluation platform for cell therapies based on brain organoidsTranslational NeurodegenerationOctober 29, 2024Jun Xue, Youjun Chu, Yanwang Huang, Ming Chen, Meng Sun, Zhiqin Fan, Yonghe Wu, Liang Chen100 ng/ml, Rocky Hill, NJ), FGF8 (PeproTech, 100–25, 100 ng/ml), and purmorphamine (MedChemExpress, HY-15108, 2 μΜ) were supplemented on days 2–10. CHIR99021 (TargetMol, T2310, 1 μΜ) was supplemented on days 4–14.

(7) A novel protocol to derive cervical motor neurons from induced pluripotent stem cells for amyotrophic lateral sclerosisStem cell reportsSeptember 12, 2023Yang M, Liu M, Sánchez YF, Avazzadeh S, Quinlan LR, Liu G, Lu Y, Yang G, O''Brien T, Henshall DC, et al.plates in NIM with 1 μM CHIR, 2 μM SB, 2 μM DMH1, 0.1 μM RA (HY-14649, MCE), and 0.5 μM purmorphamine (HY-15108, MCE) for the subsequent 6 days with medium changed every 2 days. On day 9 or 12, the patterned MNPs

(8) A role for transcription factor STAT3 signaling in oncogene smoothened-driven carcinogenesisThe Journal of biological chemistryNovember 2, 2012Gu D, Fan Q, Zhang X, Xie J.

(9) Purmorphamine enhances osteogenic activity of human osteoblasts derived from bone marrow mesenchymal cellsCell biology internationalJuly 1, 2005Beloti MM, Bellesini LS, Rosa AL.

(10) [Sample selection in biometric analysis]Fogorvosi szemleJuly 1, 1971Béky J.

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Purmorphamine from MedChemExpress

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Purmorphamine from MedChemExpress

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