Hydroxyurea from MedChemExpress

Product Specs
ItemHydroxyurea
CompanyMedChemExpress
Price $61.00Supplier Page View Company Product Page
Catalog NumberHY-B0313
Quantity10 mM * 1 mL
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.34%
TypeChemical
Molecular Weight76.05
Molecule NameHydroxyurea
FormulaCH4N2O2
Research AreaCancer

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(1) The Role of Hemoglobin in Temporomandibular Joint Osteoarthritis and the Therapeutic Potential of HydroxyureaInt J DentMay 19, 2026Min Hui, Zhihua Xu, Qinghua Li, Ying Zhan, Yuqian Shi, Fan Wu, Lei Lu, Mian Zhang, Hongxu Yang, Shibin Yu, et al.prosthesis bonding. 2.3. TMJ Injection Intra‐articular injections of HU (50 μL per side, 25 μmol/mL; HY‐B0313, MedChemExpress, NJ, USA) were administered twice weekly for 4 weeks, starting 3 days after the UAC

(2) RRM1 inhibition sensitizes lung adenocarcinoma to decitabine treatmentCell Death & DiseaseFebruary 26, 2026Nan Jiang, Jianyong Liu, Ajay Vaghasia, Nicole Anders, Michelle Rudek, William G. Nelson, Srinivasan Yegnasubramanian, Jianya Zhou#HY-10082, CAS No. 143621-35-6), clofarabine (CLO, #HY-A0005, CAS No. 123318-82-1), and hydroxyurea (HU, #HY-B0313, CAS No. 127-07-1) were purchased from MedChemExpress (MCE) chemicals. RNA interference Human-RRM1

(3) Oncometabolite fumarate impairs ATR-CHK1 signaling by succinating RPA1 in Fumarate Hydratase-deficient renal cell carcinoma cellsbioRxivDecember 10, 2025Nian Liu, Changxian Shen, Tingting Zhou, Yu Zhou, Hang Yuan, Hongjie Bi, Yingying Wang, Xinyu Pei, Rui Su, Li Zheng, et al.1:2000) HRP-linked antibodies were purchased from ThermoFisher Scientific. 2.2. Chemicals Hydroxyurea (HY-B0313), fumarate hydratase inhibitor FH-IN-1(HY-100004) were purchased from MedChemExpress. Dimethyl fumarate

(4) NRG1/PDGFC loop between fibroblasts and cancer cells drives paclitaxel resistance via ferroptosis suppression in breast cancerCell Death DiscoveryNovember 10, 2025Wan-Li Duan, Xue-Jie Wang, Li-Hui Gu, Ai Guo, Yi-Yue Ding, Ping Lin, Bao-Gang ZhangHY-B0015), ARQ 751 trihydrochloride (HY-137458A), Erastin (HY-15763), Nigericin (HY-127019), Hydroxyurea (HY-B0313), Wogonoside (HY-N0399), and PDGFRα kinase inhibitor 1 (HY-111507) were purchased from MedChemExpress

(5) The deubiquitination-PARylation positive feedback loop of the USP10-PARP1 axis promotes DNA damage repair and affects therapeutic efficacy of PARP1 inhibitorOncogeneMay 2, 2025Jingwei Liu, Siyi Zhang, Liangzi Cao, Naijin Zhang, Qiqiang Guo, Yu Zou, Ruohan Yang, Shiyuan Dong, Lixia Zheng, Yutong Xiao, et al.for Immunohistochemistry. Olaparib (SC9118), Spautin-1 (SC5498) and NAC (S0077) were purchased from Beyotime. Hydroxyurea (HY-B0313) was purchased from MedChemExpress. CHX (S7418), PDD00017273 (PARG inhibitor, S8862) and KU-55933 (ATM

(6) CAN-Scan: A multi-omic phenotype-driven precision oncology platform identifies prognostic biomarkers of therapy response for colorectal cancerCell Reports MedicineApril 15, 2025Shumei Chia, Justine Jia Wen Seow, Rafael Peres da Silva, Chayaporn Suphavilai, Niranjan Shirgaonkar, Maki Murata-Hori, Xiaoqian Zhang, Elena Yaqing Yong, Jiajia Pan, Matan Thangavelu Thangavelu, et al.HY-50896 Flutamide,MedChemExpress,Cat# HY-B0022 Gemcitabine,MedChemExpress,Cat# HY-17026 Hydroxyurea,MedChemExpress,Cat# HY-B0313 Idarubicin hydrochloride,MedChemExpress,Cat# HY-17381 lfosfamide,MedChemExpress,Cat# HY-17419 Ixabepilone,MedChemExpress,Cat#

(7) Deubiquitination of CDC6 by OTUD6A promotes tumour progression and chemoresistanceMolecular CancerApril 29, 2024Jianfeng Cui, Xiaochen Liu, Qinghong Shang, Shuna Sun, Shouzhen Chen, Jianping Dong, Yaofeng Zhu, Lei Liu, Yangyang Xia, Yong Wang, et al.at 37 ℃ in an incubator with 5% CO2. MG132 (HY-13,259), cycloheximide (HY-12,320), hydroxyurea (HU, HY-B0313), gemcitabine (HY-17,026), methotrexate (HY-14,519), chloroquine (HY-17,589 A), CVT-313 (HY-15,339),

(8) A loss-of-function variant in ZCWPW1 causes human male infertility with sperm head defect and high DNA fragmentationReproductive HealthFebruary 3, 2024Yuelin Song, Juncen Guo, Yanling Zhou, Xingjian Wei, Jianlan Li, Guohui Zhang, Hongjing WangpCAG plasmid. After 24 h, HEK293T cells were treated with culture medium added with 2 mM hydroxyurea (HY-B0313, MedChemExpress) for 12 h. The slides were coated with 80ul 0.8% normal-gelling agarose first. A total

(9) DEPTOR is a direct p53 target that suppresses cell growth and chemosensitivityCell death & diseaseNovember 12, 2020Cui D, Dai X, Gong L, Chen X, Wang L, Xiong X, Zhao Y.sources: bleomycin (HY-17565; MCE, Monmouth Junction, NJ, USA), mitomycin C (HY-13316; MCE), hydroxyurea (HY-B0313; MCE), methotrexate (HY-14519; MCE), cyclophosphamide (HY-17420; MCE), teniposide (HY-13761; MCE), nutlin-3

(10) Oncogene PRR14 promotes breast cancer through activation of PI3K signal pathway and inhibition of CHEK2 pathwayCell death & diseaseJune 15, 2020Ren X, Long M, Li Z, Wu B, Jin T, Tu C, Qi L, Yang M.HY-13629, MCE), 5-fluorouracil (5-FU, HY-90006, MCE), H2O2 (88597, Millipore) and hydroxyurea (HU, HY-B0313, MCE), were used to treat cells. Complementary DNA encoding full-length human PRR14 was cloned into

(11) Hydroxyurea (therapeutics and mechanism): metabolism, carbamoyl nitroso, nitroxyl, radicals, cell signaling and clinical applicationsMedical hypothesesJanuary 1, 2011Kovacic P.

(12) Hydroxyurea therapy requires HbF induction for clinical benefit in a sickle cell mouse modelHaematologicaSeptember 1, 2010Lebensburger JD, Pestina TI, Ware RE, Boyd KL, Persons DA.

(13) In vivo and in vitro studies of fetal hemoglobin induction by hydroxyurea in beta-thalassemia/hemoglobin E patientsExperimental hematologyDecember 1, 2005Watanapokasin Y, Chuncharunee S, Sanmund D, Kongnium W, Winichagoon P, Rodgers GP, Fucharoen S.

(14) Rationale for the use of hydroxyurea as an anti-human immunodeficiency virus drugClinical infectious diseases : an official publication of the Infectious Diseases Society of AmericaJune 1, 2000Lori F, Lisziewicz J.

(15) Hydroxyurea-resistant vaccinia virus: overproduction of ribonucleotide reductaseJournal of virologyNovember 1, 1986Slabaugh MB, Mathews CK.

(16) Myosin from starfish egg: properties and interaction with actinJournal of molecular biologyFebruary 5, 1976Mabuchi I.

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Hydroxyurea from MedChemExpress

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Hydroxyurea from MedChemExpress

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