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Protein Biochemistry
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Apigenin
Apigenin from MedChemExpress
Be the first to write a review!
Citations:
(16)
Supplier Page
Supplier Page from
MedChemExpress for
Apigenin
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Description
Apigenin (4',5,7-Trihydroxyflavone) is a competitive
CYP2C9
inhibitor with a
K
i
of 2 µM
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Apigenin
Company
MedChemExpress
Price
$61.00
Supplier Page
View Company Product Page
Catalog Number
HY-N1201
Quantity
10 mM * 1 mL
Applications
Bioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity
99.22%
Type
Chemical
Molecular Weight
270.24
Formula
C₁₅H₁₀O₅
Research Area
Inflammation/Immunology; Cancer
Add to Compare List
MedChemExpress
1 Deer Park Drive, Suite F
MONMOUTH JUNCTION
,
NJ
08852
United States
Phone
: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910
Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com
Company Profile
Website:
medchemexpress.com
Citations (16)
(1)
A biomimetic tubuloid-on-a-chip for human renal fibrosis research and anti-fibrotic drug development
J Tissue Eng
July 24, 2026
Xinyu Zhang, Feili Yang, Cheng Han, Yina Wang, Xueqiang Liu, Zhonghang Wang, Jichun Suo, Huimin Long, Libin Zhou, Zilin Zhang,
et al.
During the low-glucose preconditioning period, SGLT2
inhibitors
(apigenin: 100 μM and 200 μM,
MCE
,
HY-N1201
, USA; dapagliflozin: 40 μM,
Selleck
,
S1548
, USA) were dissolved in low-glucose medium when required
(2)
Multi-omics reveals molecular signatures of moderate intensity exercise and identifies candidate exercise mimetics in mice
Redox Biol
April 22, 2026
Hanlin Jiang, Shota Inoue, Junpei Hatakeyama, Hideki Moriyama
received daily oral gavage of six candidate compounds at low and high doses: apigenin (10 or 50 mg/kg/day;
HY-N1201
,
MedChemExpress
, Monmouth Junction, NJ, USA), doxazosin (1 or 10 mg/kg/day; S5782, Selleck Chemicals,
(3)
PTGS2 as a potential target for apigenin to promote spinal cord injury repair
Journal of Bioenergetics and Biomembranes
March 18, 2026
Jialin Zhang, Min Zhao
(https://www.omicstudio.cn/tool) (Lyu et al. 2023).
Cell culture
and drug Apigenin, purchased from
MedChemExpress
(
HY-N1201
, purity > 99.5%), was dissolved in
Dimethyl sulfoxide
. Compared to other SCI
in vitro
models, the H₂O₂-induced
(4)
Apigenin Alleviates Zearalenone-Induced Oxidative Stress and Apoptosis in Swine Testis Cells Through the Wnt Signaling Pathway
Antioxidants (Basel)
December 29, 2025
Chenyun Guo, Yidan Zhang, Yiwei Wang, Yile Sun, Haoze Ning, Jiaxin Gao, Fei Guo, Pengyun Ji, Lu Zhang, Guoshi Liu,
et al.
alleviates ZEN-induced
injury
in ST cells. 2. Materials and Methods 2.1. Chemicals and Reagents AP (
HY-N1201
) and ZEN (
HY-103447
) were purchased from
MedChemExpress
(MCE, Shanghai, China). The Wnt pathway
inhibitor
(5)
Apigenin Suppresses NLRP3 Inflammasome Activation and Pyroptosis and Promotes Functional Recovery by Promoting Mitophagy in Experimental Spinal Cord Injured Rats
J Inflamm Res
October 8, 2025
Zuomeng Wu, Yunxiao Fang, Yixiang Dong, Yue Qin, Ao Liu, Tianyu Han, Peiwen Song, Cailiang Shen
expression. In the Sham group, only
laminectomy
was performed without
spinal cord compression
.
API
(
MCE
,
HY-N1201
, USA) was dissolved in 10% dimethyl sulfoxide (DMSO) (BS087, Biosharp, China), and SCI
rats
were intraperitoneally
(6)
Apigenin Suppresses NLRP3 Inflammasome Activation and Pyroptosis and Promotes Functional Recovery by Promoting Mitophagy in Experimental Spinal Cord Injured Rats
J Inflamm Res
October 8, 2025
Zuomeng Wu, Yunxiao Fang, Yixiang Dong, Yue Qin, Ao Liu, Tianyu Han, Peiwen Song, Cailiang Shen
expression. In the Sham group, only
laminectomy
was performed without
spinal cord compression
.
API
(
MCE
,
HY-N1201
, USA) was dissolved in 10% dimethyl sulfoxide (DMSO) (BS087, Biosharp, China), and SCI
rats
were intraperitoneally
(7)
Apigenin Inhibits Cell Ferroptosis by Activating the PI3K/Akt Pathway and Alleviates Renal Injury Caused by Hypertension
Dose Response
May 24, 2025
Haina Zhang, Yanhua Cao, Liting Jiao, Jianwei Wan
infusion, the
mice
in the
API
group were intraperitoneally injected with
API
(Apigenin, 20 mg/kg/day,
HY-N1201
,
MedChemExpress
) once daily for 28 continuous days, 10 while the
mice
in the control and Ang II groups
(8)
Rescue of Mutant CFTR Channel Activity by Investigational Co-Potentiator Therapy
Biomedicines
January 1, 2025
Mafalda Bacalhau, Filipa C. Ferreira, Marcelo Folhadella M. F. Azevedo, Talita P. Rosa, Camilla D. Buarque, Miquéias Lopes-Pacheco
purchased from
MedChemExpress
(Monmouth Junction, NJ, USA) at the highest purity available: apigenin (#
HY-N1201
), ABBV-974 (#
HY-111099
), ABBV-3067 (#
HY-109152
), VX-770 (#
HY-13017
), forskolin (Fsk; #
HY-15371
), and
(9)
Apigenin attenuates ischemia-reperfusion-induced pulmonary ferroptosis and fibrosis by activating the Nrf2/HO-1/GPX4 axis in mice
Turk J Biol
October 18, 2024
Liang Zhang, Haojie Li, Shichen Xu, Hao Wen, Chaoxiao Yu
restored over the 2 h after the vascular clamp was loosened. APG was obtained from
MedChemExpress
(#
HY-N1201
), and a stock solution of 5 mM was prepared in
dimethyl sulfoxide (DMSO
, #
D2650
,
Sigma-Aldrich
). The
(10)
Neuroprotective effects of apigenin on retinal ganglion cells in ischemia/reperfusion: modulating mitochondrial dynamics in in vivo and in vitro models
Journal of Translational Medicine
May 13, 2024
Jiawen Wu, Daowei zhang, Hongli Liu, Jufeng Li, Ting Li, Jihong Wu, Shenghai Zhang
one eye of each
rat
. A detailed diagram was shown in Fig. 1.
Intravitreal injection
API
(Item No.
HY-N1201
) with purity higher than 99% was purchased from
MCE
, dissolved in DMSO to a stock concentration of 100
(11)
LINC00629, a KLF10-responsive lncRNA, promotes the anticancer effects of apigenin by decreasing Mcl1 stability in oral squamous cell carcinoma
Aging
November 28, 2022
Shi C, Ma C, Ren C, Li N, Liu X, Zhang Y, Wang Y, Li X, Lv P, Han C,
et al
.
no.
SC-47721
,
1:1000
), anti-KLF10 antibody (
GeneTex
, Cat. no.
GTX108661
,
1:200
), apigenin (Cat. no.
HY-N1201
,
MedChemExpress
). ALDH1-positive cell detection and sphere formation
assay
The ALDH1-positive population
(12)
Apigenin suppresses PD-L1 expression in melanoma and host dendritic cells to elicit synergistic therapeutic effects
Journal of experimental & clinical cancer research : CR
October 29, 2018
Xu L, Zhang Y, Tian K, Chen X, Zhang R, Mu X, Wu Y, Wang D, Wang S, Liu F,
et al
.
obtained from Proteintech. Recombinant human interferon-γ (IFN-γ) was from T&L Biotechnology. Apigenin (
HY-N1201
) and curcumin (
HY-N0005
) were purchased from
MCE
.
Cell viability assay
The proliferation of
melanoma
(13)
Apigenin Attenuates Adriamycin-Induced Cardiomyocyte Apoptosis via the PI3K/AKT/mTOR Pathway
Evidence-based complementary and alternative medicine : eCAM
January 1, 2017
Yu W, Sun H, Zha W, Cui W, Xu L, Min Q, Wu J.
(14)
Mechanism of CYP2C9 inhibition by flavones and flavonols
Drug metabolism and disposition: the biological fate of chemicals
March 1, 2009
Si D, Wang Y, Zhou YH, Guo Y, Wang J, Zhou H, Li ZS, Fawcett JP.
(15)
Inhibitory effects of apigenin on the growth of gastric carcinoma SGC-7901 cells
World journal of gastroenterology
August 7, 2005
Wu K, Yuan LH, Xia W.
(16)
A contribution to the study of Hodgkin's disease: a late follow-up
The British journal of surgery
May 1, 1971
Patey DH.
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Apigenin from MedChemExpress
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$61.00
Product Specs
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