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Protein Biochemistry
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TGX-221
TGX-221 from MedChemExpress
Be the first to write a review!
Citations:
(8)
Supplier Page
Supplier Page from
MedChemExpress for
TGX-221
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Description
TGX-221 is a potent, selective, and cell membrane permeable inhibitor of the
PI3K p110β
catalytic subunit, used for cancer treatment
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
TGX-221
Company
MedChemExpress
Price
$75.00
Supplier Page
View Company Product Page
Catalog Number
HY-10114
Quantity
10 mM * 1 mL
Applications
Bioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity
99.74%
Type
Chemical
Molecular Weight
364.44
Formula
C₂₁H₂₄N₄O₂
Research Area
Cancer
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MedChemExpress
1 Deer Park Drive, Suite F
MONMOUTH JUNCTION
,
NJ
08852
United States
Phone
: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910
Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com
Company Profile
Website:
medchemexpress.com
Citations (8)
(1)
NK cell-related genes-driven novel molecular subtyping and prognostic signatures for Wilms tumor: uncovering the therapeutic potential of TGX-221 and biomarker role of HS2ST1
Frontiers in Oncology
August 28, 2025
Peng Hong, Zaihong Hu, Jie Lin, Kongkong Cui, Zhiqiang Gao, Xiaomao Tian, Tao Lin, Qinlin Shi, Guanghui Wei
maintained at the Chongqing Key Laboratory of Structural
Birth Defects
and Organ Reconstruction.
TGX-221
(
HY-10114
,
MedChemExpress
) was dissolved in DMSO and assessed for cytotoxicity via CCK-8
assays
(
HY-K0301
), where
(2)
Oncogenic PIK3CA corrupts growth factor signaling specificity
Molecular Systems Biology
December 20, 2024
Ralitsa R Madsen, Alix Le Marois, Oliwia N Mruk, Margaritis Voliotis, Shaozhen Yin, Jahangir Sufi, Xiao Qin, Salome J Zhao, Julia Gorczynska, Daniele Morelli,
et al.
strip tubes and stored at −80 °C long-term (up to 2 years). TGX221 was obtained from
MedChemExpress
(#
HY-10114
) and reconstituted at 10 mM in sterile DMSO, prior to long-term storage (up to 3 years) at −80 °C. 1938
(3)
The phosphoinositide 3'-kinase p110δ modulates contractile protein production and IL-6 release in human airway smooth muscle
Journal of cellular physiology
August 1, 2012
Ge Q, Moir LM, Trian T, Niimi K, Poniris M, Shepherd PR, Black JL, Oliver BG, Burgess JK.
(4)
Prodrug strategy for PSMA-targeted delivery of TGX-221 to prostate cancer cells
Molecular pharmaceutics
June 4, 2012
Zhao Y, Duan S, Zeng X, Liu C, Davies NM, Li B, Forrest ML.
(5)
Role of protein kinase C and epidermal growth factor receptor signalling in growth stimulation by neurotensin in colon carcinoma cells
BMC cancer
October 2, 2011
Müller KM, Tveteraas IH, Aasrum M, Ødegård J, Dawood M, Dajani O, Christoffersen T, Sandnes DL.
(6)
Advantages of a selective beta-isoform phosphoinositide 3-kinase antagonist, an anti-thrombotic agent devoid of other cardiovascular actions in the rat
European journal of pharmacology
June 10, 2008
Sturgeon SA, Jones C, Angus JA, Wright CE.
(7)
Evidence for functional redundancy of class IA PI3K isoforms in insulin signalling
The Biochemical journal
June 15, 2007
Chaussade C, Rewcastle GW, Kendall JD, Denny WA, Cho K, Grønning LM, Chong ML, Anagnostou SH, Jackson SP, Daniele N,
et al
.
(8)
Oscillatory phenomena in kinetic antipercolation
Physical review. A, Atomic, molecular, and optical physics
January 15, 1992
Wu K, Bradley RM.
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TGX-221 from MedChemExpress
Supplier Page
View Company Product Page
$75.00
Product Specs
Company Info
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