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Protein Biochemistry
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Selitrectinib
Selitrectinib from MedChemExpress
Be the first to write a review!
Citations:
(3)
Supplier Page
Supplier Page from
MedChemExpress for
Selitrectinib
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Description
Selitrectinib (LOXO-195) is a next-generation
TRK kinase
inhibitor, with
IC
50
s of 0.6 nM and <2.5 nM for
TRKA
and
TRKC
, respectively
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Selitrectinib
Company
MedChemExpress
Price
$110.00
Supplier Page
View Company Product Page
Catalog Number
HY-101977
Applications
Bioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity
99.90%
Formula
C20H21FN6O
Research Area
Cancer
Type
Chemical
Molecular Weight
380.42
Quantity
10 mM * 1 mL
Molecule Name
Selitrectinib
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MedChemExpress
1 Deer Park Drive, Suite F
MONMOUTH JUNCTION
,
NJ
08852
United States
Phone
: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910
Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com
Company Profile
Website:
medchemexpress.com
Citations (3)
(1)
A novel TRKB-activating internal tandem duplication characterizes a new mechanism of receptor tyrosine kinase activation
NPJ Precis Oncol
May 10, 2025
Lauren M. Brown, Gabor Tax, Pablo Acera Mateos, Antoine de Weck, Steve Foresto, Thomas Robertson, Fatimah Jalud, Pamela Ajuyah, Paulette Barahona, Jie Mao,
et al.
number
Larotrectinib
,Trk Receptor,
MedChemExpress
,
HY-12866A
Selitrectinib
,Trk Receptor,
MedChemExpress
,
HY-101977
Entrectinib
,ALK; ROS; Trk Receptor,
MedChemExpress
,
HY-12678
Repotrectinib
,ALK; ROS; Trk Receptor,
MedChemExpress
,
HY-103022
Trametinib
,MEK,
MedChemExpress
,
HY-10999
Pimasertib
,MEK,
MedChemExpress
,
HY-12042
Paxalisib
,mTOR;
(2)
The Impact of ETV6-NTRK3 Oncogenic Gene Fusions on Molecular and Signaling Pathway Alterations
Cancers (Basel)
August 24, 2023
Matias Kinnunen, Xiaonan Liu, Elina Niemelä, Tiina Öhman, Lisa Gawriyski, Kari Salokas, Salla Keskitalo, Markku Varjosalo
three treatments: 2 μg/mL tetracycline and 100 mM
inhibitor
Selitrectinib/LOXO-195 (
MedChemExpress
#
HY-101977
, South Brunswick Township, NJ, USA), 2 μg/mL tetracycline and DMSO equivalent of
inhibitor
or low-glucose
(3)
A Next-Generation TRK Kinase Inhibitor Overcomes Acquired Resistance to Prior TRK Kinase Inhibition in Patients with TRK Fusion-Positive Solid Tumors
Cancer discovery
September 1, 2017
Drilon A, Nagasubramanian R, Blake JF, Ku N, Tuch BB, Ebata K, Smith S, Lauriault V, Kolakowski GR, Brandhuber BJ,
et al
.
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Selitrectinib from MedChemExpress
Supplier Page
View Company Product Page
$110.00
Product Specs
Company Info
Citations
Reviews
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