QL47 from MedChemExpress | Biocompare.com

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QL47

Description

QL47, a broad-spectrum antiviral agent, inhibits dengue virus and other RNA viruses. QL47 selectively inhibits eukaryotic translation. QL47 is a potent covalent inhibitor of BTK with an IC₅₀ of 7 nM

Product Specs
ItemQL47
CompanyMedChemExpress
Price $168.00Supplier Page View Company Product Page
Catalog NumberHY-80003
Quantity5 mg
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.50%
TypeChemical
Molecular Weight447.49
FormulaC₂₇H₂₁N₅O₂
Research AreaInfection; Cancer

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(1) A broad-spectrum antiviral molecule, QL47, selectively inhibits eukaryotic translationThe Journal of biological chemistryFebruary 7, 2020de Wispelaere M, Carocci M, Burri DJ, Neidermyer WJ Jr, Olson CM, Roggenbach I, Liang Y, Wang J, Whelan SPJ, Gray NS, et al.

(2) Structure-Activity Relationship Study of QL47: A Broad-Spectrum Antiviral AgentACS medicinal chemistry lettersMarch 9, 2017Liang Y, de Wispelaere M, Carocci M, Liu Q, Wang J, Yang PL, Gray NS.

(3) Discovery of a potent, covalent BTK inhibitor for B-cell lymphomaACS chemical biologyMay 16, 2014Wu H, Wang W, Liu F, Weisberg EL, Tian B, Chen Y, Li B, Wang A, Wang B, Zhao Z, et al.

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