MMAF from MedChemExpress

Product Specs
ItemMMAF
CompanyMedChemExpress
Price $50.00Supplier Page View Company Product Page
Catalog NumberHY-15579
Quantity5 mg
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.96%
TypeChemical
Molecular Weight731.96
FormulaC₃₉H₆₅N₅O₈
Research AreaCancer

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(1) Liquid tumor microenvironment enhances WNT signaling pathway of peritoneal metastasis of gastric cancerScientific ReportsJuly 10, 2023Huawei Xu, Zhibin Hao, Yujie Wang, Deng Zhang, Jie Li, Ling Chen, Ninghua Yao, Binbin Qian, Xiaobo Peng, Xianbao Zhanwell contained about 200 ± 50 MADOs in 15 mL matrigel with 300 mL culture medium. Salinomycin (MCE, HY-15579) and porcupine inhibitor (Porcn-IN-1, MCE, HY-111472) were prepared in MADOs medium according to the

(2) Payload-binding Fab fragments increase the therapeutic index of MMAE antibody-drug conjugatesMol Cancer TherApril 3, 2023Brandon M. Bordeau, Toan Duc Nguyen, Joseph Ryan Polli, Ping Chen, Joseph P. Balthasarapproved by the University at Buffalo Institutional Animal Care and Use Committee. MMAE (HY-15162), MMAF (HY15579), d8-MMAE (HY-15162A) and vc-MMAE (HY-15575) were purchased from MedChemExpress (Monmouth Junction,

(3) Payload-Binding Fab Fragments Increase the Therapeutic Index of MMAE Antibody–Drug ConjugatesMolecular Cancer TherapeuticsApril 3, 2023Brandon M. Bordeau, Toan Duc Nguyen, Joseph Ryan Polli, Ping Chen, Joseph P. Balthasarapproved by the University at Buffalo Institutional Animal Care and Use Committee. MMAE (HY-15162), MMAF (HY15579), d8-MMAE (HY-15162A) and vc-MMAE (HY-15575) were purchased from MedChemExpress (Monmouth Junction,

(4) Strategies and Advancement in Antibody-Drug Conjugate Optimization for Targeted Cancer TherapeuticsBiomolecules & therapeuticsNovember 1, 2015Kim EG, Kim KM.

(5) Enzymatic prenylation and oxime ligation for the synthesis of stable and homogeneous protein-drug conjugates for targeted therapyAngewandte Chemie (International ed. in English)October 5, 2015Lee JJ, Choi HJ, Yun M, Kang Y, Jung JE, Ryu Y, Kim TY, Cha YJ, Cho HS, Min JJ, et al.

(6) EphA2 targeted chemotherapy using an antibody drug conjugate in endometrial carcinomaClinical cancer research : an official journal of the American Association for Cancer ResearchMay 1, 2010Lee JW, Stone RL, Lee SJ, Nam EJ, Roh JW, Nick AM, Han HD, Shahzad MM, Kim HS, Mangala LS, et al.

(7) Enhanced activity of monomethylauristatin F through monoclonal antibody delivery: effects of linker technology on efficacy and toxicityBioconjugate chemistryJanuary 1, 2006Doronina SO, Mendelsohn BA, Bovee TD, Cerveny CG, Alley SC, Meyer DL, Oflazoglu E, Toki BE, Sanderson RJ, Zabinski RF, et al.

(8) Clinical relevance of pRb and p53 co-overexpression in soft tissue sarcomasCancer lettersMay 24, 1999Würl P, Meye A, Lautenschläger C, Schmidt H, Bache M, Kalthoff H, Schönfelder M, Rath FW, Taubert H.

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MMAF from MedChemExpress

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