Progesterone from MedChemExpress

Product Specs
ItemProgesterone
CompanyMedChemExpress
Price $73.00Supplier Page View Company Product Page
Catalog NumberHY-N0437
Quantity10 mM * 1 mL
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.79%
TypeChemical
Molecular Weight314.46
FormulaC₂₁H₃₀O₂
Research AreaCardiovascular Disease; Cancer

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(1) Diurnal testosterone oscillations gate drug delivery via phase separation of ZO-1 at the blood-testis barrier in miceCommunications BiologyJune 1, 2026Zhaoyang Wang, Qihong Wu, Xun Tang, Lu Li, Jingxian Deng, Rufei Huang, Wanqing Lin, Yadong Huang, Yan Yangmg/mouse; MedChemExpress; HY-B1192) 24 h prior, followed by progesterone (500 μg/kg; MedChemExpress; HY-N0437) 4 h before the trial. This ensured all females were in estrus at the time of pairing. Treated male

(2) Mitochondrial Function Under Combined Oral Contraceptive Exposure in a Neuroblastoma Model: A Preliminary InvestigationBiomedicinesMay 7, 2026Francesco Chiara, Sarah Allegra, Francesco Maximillian Anthony Shelton Agar, Giuliana Abbadessa, Silvia De Franciainterpreting mitochondrial responses. 2. Materials and Methods 2.1. Reagents and Solutions P4 (HY-N0437), E2 (HY-B0141), DNG (HY-B0084), and EE (HY-B0216) were standard-grade and purchased from MedChemExpress

(3) Multiparity exacerbates Aβ accumulation and promotes cellular senescence in a mouse model of amyloidosisImmunity & AgeingMarch 29, 2026Renzhi Yang, Ying He, Youkai Pan, Aoyi Geng, Fang Huang, Kai Guo, Hongsheng Zhangdays of treatment with 200 nM estradiol (E2) (Sigma Aldrich, E2758), 200 nM progesterone (P4) (MCE, HY-N0437), followed by BCA quantification (Thermo Fisher Scientific, A55864) and western blot analysis. Antibodies The

(4) Gestational progesterone restores menstrual cycle in PCOS patients via enhancing ovary estrogen productionLife MetabolismFebruary 2, 2026Qiwen Yang, Na Kong, Jing Wu, Yan Yang, Xinge Zhang, Yuan Lin, Zhibin Hu, Guijun Yan, Haixiang Sun, Chaojun Lirandomly divided into two groups and injected daily intraperitoneally (i.p.) with 2 mg progesterone (MCE, HY-N0437) dissolved in sesame oil (Prog group) or sesame oil alone (control group) for 21 days. E2 (MCE, HY-B0141)

(5) Targeting the CD47-HCK-LGALS9 axis disrupts proliferation-immunosuppression coupling in early-stage endometrial cancerMolecular CancerDecember 23, 2025Jingxuan Ye, Yitong Yan, Xiaoqi Sun, Qibin Wu, Yashi Shi, Maotong Zhang, Xite Lin, Yuan Ren, Xiaodan Mao, Mingyan Lin, et al.Sino Biological, China) at 50 ng/mL; GSK5182 (#SML3150, Germany) at 10, 20, and 30 µM; progesterone (#HY-N0437, MCE, USA); and estradiol (#HY-B0141, MCE, USA). All treatments were applied for 24 h. Regulation of

(6) Depletion of Sorcs3 Activates Totipotency in Mouse Embryonic Stem Cells by Modulating Key Signaling PathwaysAdvanced ScienceNovember 3, 2025Wenhao Zhang, Xinyu Mao, Yu He, Qingshen Jia, Yiding Zhao, Xiaomeng Dai, Xiaoyan Li, Shengyi Sun, Xiaoyan Sheng, Dan Ding, et al.ITS‐X (Thermo, 12634020), 8 nm β‐mercaptoethanol (Thermo, 21985023), 200 ng mL−1 progesterone (MCE, HYN0437), and 25 µm N‐acetyl‐l‐cysteine (MCE, HY‐B0215). IVC2 medium contained Advanced DMEM/F12 supplemented

(7) Thymol Mitigates Oxidative Stress-Induced Ovarian Aging and Restores Steroidogenesis via the JAK1–STAT3 PathwayCurrent Issues in Molecular BiologyNovember 2, 2025Junjie Deng, Chen Luo, Chen Xie, Heng Duanmedium (3 mg/mL) and low (1.5 mg/mL) concentrations were prepared in the same manner. Progesterone (HY-N0437, MedChemExpress, Monmouth Junction, NJ, USA) was initially dissolved in Dimethyl sulfoxide (DMSO). After

(8) The Establishment of 3D Polarity-Reversed Organoids From Human Endometrial Tissue as a Model for Infection-Induced EndometritisBIO-PROTOCOLJune 20, 2025Xin Zhang, Li Zhang, Linyuan Fan, Zhaohui Liunumber: 12634028) 21. Estradiol (MCE, catalog number: HY-B0141) 22. Progesterone (MCE, catalog number: HY-N0437) Solutions 1. Endometrial organoid culture medium (see Recipes) 2. Collagenase type IV (2× and 1× solutions)

(9) The Establishment of 3D Polarity-Reversed Organoids From Human Endometrial Tissue as a Model for Infection-Induced EndometritisBio ProtocJune 20, 2025Xin Zhang, Li Zhang, Linyuan Fan, Zhaohui Liunumber: 12634028) 21. Estradiol (MCE, catalog number: HY-B0141) 22. Progesterone (MCE, catalog number: HY-N0437) Solutions 1. Endometrial organoid culture medium (see Recipes) 2. Collagenase type IV (2× and 1× solutions)

(10) Comparative analysis of organoid, air-liquid interface, and direct infection models for studying pathogen-host interactions in endometrial tissueSci RepMarch 12, 2025Xin Zhang, Linyuan Fan, Li Zhang, Zhaohui Liufor 3 d. Following this, organoids were treated with either 10nM E2 and 1µM P4 (Progesterone, MCE, HY-N0437) (E2 + P4), 10nM E2, for a further 4 d. Each treatment was performed in triplicate wells with a fourth

(11) Capture of Totipotency in Mouse Embryonic Stem Cells in the Absence of Pdzk1Advanced science (Weinheim, Baden-Wurttemberg, Germany)February 1, 2025Zhang W, Zhao Y, Yang Z, Yan J, Wang H, Nie S, Jia Q, Ding D, Tong C, Zhang XO, et al.penicillin‒streptomycin, 1×ITS‐X (Thermo, 12634020), 8 nm β‐mercaptoethanol (MCE, HYB0141), 200 ng ml−1 progesterone (MCE, HYN0437) and 25 µm N‐acetyl‐l‐cysteine (MCE, HY‐B0215). IVC2 medium contained DMEM/F12 supplemented with 30%

(12) Investigating bacteria-induced inflammatory responses using novel endometrial epithelial gland organoid modelsFrontiers in Reproductive HealthNovember 12, 2024Xin Zhang, Li Zhang, Ting Li, Zhan Zhang, Xiang Shang, Huihui Bai, Yong Liu, Xiaonan Zong, Chenguang Shang, Dan Song, et al.3 days. Following this, organoids were treated with either 10 nM E2 and 1 μM P4 (Progesterone, MCE, HY-N0437) (E2 + P4), 10 nM E2, for a further 4 days. Each treatment was performed in triplicate wells with a

(13) Coronavirus envelope protein activates TMED10-mediated unconventional secretion of inflammatory factorsNature communicationsOctober 8, 2024Liu L, Zhang L, Hao X, Wang Y, Zhang X, Ge L, Wang P, Tian B, Zhang M.Hydroxyprogesterone caproate (S4674), Dichlorophen (S5724) all purchased from Selleck, Ulipristal acetate (MEC, HY-N0437) and Progesterone analogs all purchased from MCE. The antibodies used in this study were obtained from

(14) Modulation of innate immune response to viruses including SARS-CoV-2 by progesteroneSignal transduction and targeted therapyApril 25, 2022Su S, Hua D, Li JP, Zhang XN, Bai L, Cao LB, Guo Y, Zhang M, Dong JZ, Liang XW, et al.inflammatory response. Materials and methods Reagents, antibodies, viruses, and cells Progesterone (HY-N0437) and Dasatinib (HY-10181) (MedChemExpress); IFN-γ (300-02, Peptech); Anti-mouse IFNAR-1-in vivo (clone

(15) Tilianin attenuates MPP(+)-induced oxidative stress and apoptosis of dopaminergic neurons in a cellular model of Parkinson''s diseaseExperimental and therapeutic medicineApril 1, 2022Li J, Xu S.solution (ITS-A; cat. no. 51300044; Thermo Fisher Scientific, Inc.), 0.315 mg/ml progesterone (cat. no. HY-N0437; MedChemExpress) and 20 mg putrescine (cat. no. HY-N2407; MedChemExpress), in addition to 100 U/ml penicillin/streptomycin

(16) Licorice zinc suppresses melanogenesis via inhibiting the activation of P38MAPK and JNK signaling pathway in C57BL/6J mice skinActa cirurgica brasileiraJanuary 1, 2022Wang JY, Xie XY, Deng Y, Yang HQ, Du XS, Liu P, Du Y.

(17) Progesterone pharmacokinetics in the mouse: implications for potential stroke therapyThe Journal of pharmacy and pharmacologyNovember 1, 2012Wong R, Ray D, Kendall DA.

(18) Progesterone, but not estrogen, stimulates vessel maturation in the mouse endometriumEndocrinologyNovember 1, 2007Girling JE, Lederman FL, Walter LM, Rogers PA.

(19) Classification and pharmacology of progestinsMaturitasDecember 10, 2003Schindler AE, Campagnoli C, Druckmann R, Huber J, Pasqualini JR, Schweppe KW, Thijssen JH.

(20) Effects of wild yam extract on menopausal symptoms, lipids and sex hormones in healthy menopausal womenClimacteric : the journal of the International Menopause SocietyJune 1, 2001Komesaroff PA, Black CV, Cable V, Sudhir K.

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Progesterone from MedChemExpress

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