ML-210 from MedChemExpress

Product Specs
ItemML-210
CompanyMedChemExpress
Price $104.00Supplier Page View Company Product Page
Catalog NumberHY-100003
Quantity10 mM * 1 mL
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.93%
TypeChemical
Molecular Weight475.32
FormulaC₂₂H₂₀Cl₂N₄O₄
Research AreaCancer

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(1) Loss of heterozygosity exposes germline mutations in complex I and drives Warburg metabolism in oncocytic carcinoma of the thyroidSci AdvJuly 3, 2026Celia de la Calle Arregui, Anderson R. Frank, Kelvin Mun, Jiwoong Kim, Kuntal Majmudar, Justin A. Bishop, Cheryl Lewis, Yang Xie, David G. McFaddenaspirated and replaced with 200 μl of fresh medium. CB839 (Selleckchem, #S7655) or ML210 (MedChemExpress, #HY-100003) was added as a threefold serial dilution using a D300e Digital Dispenser (Tecan). Following 72 hours

(2) TGM2-mediated serotonylation of GPX4 confers ferroptosis resistance to promote gastric tumorigenesisCell DiscovApril 28, 2026Junping Bai, Dandan Geng, Xinwen Chen, Wanting Li, Xiaowei Wang, Luyang Tian, Yi Han, Zhao Jin, Meihang Du, Yang Tang, et al.with the indicated concentrations of 5-HT (Sigma‒Aldrich, H9523), RSL3 (Selleck, S8155), ML-210 (MCE, HY-100003), SB 204741 (MCE, HY-103153), or ERW1041E (Sigma‒Aldrich, 509522) for 24 h. For the colony formation

(3) mTORC1 activity suppresses ferroptosis through a SCARB1-dependent HDL-tocopherol uptake pathwayMolecular CellApril 16, 2026Thomas A. O’Loughlin, John S. Stiles, Pritika Acharya, Abolfazl Arab, Laine Goudy, Raymond Dai, Ashir A. Borah, William A. Weiss, Uche N. Medoh, Luke A. Gilberterastin (# S8877), and Trolox (# S3665) were from Selleck Chemicals; Sapanisertib (# HY-13328), ML210 (# HY-100003), FIN56 (# HY-103087), and Ferrostatin-1 (# HY-100579) were all obtained from MedChemExpress; BSO (#

(4) Systematic Evaluation Defines the Limits of Ferroptosis in Cancer TherapybioRxivMarch 17, 2026Kenji M. Fujihara, Azmi Aziz, Behnia Akbari, Maria Gutierrez-Perez, Gregory Francis, Siham Zentout, Kameng Wu, Nicholas J. Clemons, Erdem M. Terzi, Michael E. Pacold, et al.(214485, Sigma), doxycycline (J60579.22, LifeSciences), ML-162 (HY-100002, MedChemExpress) ML-210 (HY-100003, MedChemExpress), DTT (D0632, Sigma), TCEP (C4706, Sigma), U-13C-serine (CLM-1574-H, Cambridge Isotopes),

(5) ERM Inhibition Confers Ferroptosis Resistance through ROS‐Induced NRF2 SignalingAdvanced ScienceMarch 1, 2026Menghao Qiao, Liqun Zhou, Minhua Zhou, Yu Fang, Haiying Mai, Lingbo Cao, Kun Xu, Yuan Sang, Minyi Chen, Jiewei Huang, et al.#T4360); Zinc Protoporphyrin IX (ZnPP, MCE, #HY‐101193); (1S, 3R)‐RSL3 (Selleck, #S8155); ML210 (MCE, #HY‐100003); Cytochalasin D (CytoD, Glpbio, #GC13440); tert‐butyl hydroperoxide (tBOOH, MACKLIN, #B802372‐50 mL);

(6) ΔNp73 isoform defines a TP53-mutant-like poor-risk subgroup of acute myeloid leukemiaCell Reports MedicineJanuary 20, 2026Diego A. Pereira-Martins, Cesar Ortiz, Isabel Weinhäuser, Albertus T.J. Wierenga, Vincent van den Boom, Fatemeh Mojallali, Dominique Sternadt, Nisha K. van der Meer, Shanna M. Hogeling, Thiago M. Bianco, et al.Guanfacine hydrochloride,MedChemExpress,HY-17416 Dipyridamole,MedChemExpress,HY-B0312R MK-8245,MedChemExpress,HY-13070 "RSL3 ((1S,3R)-RSL3)",MedChemExpress,HY-100218A ML-210,MedChemExpress,HY-100003 Eprenetapopt (APR-246),MedChemExpress,HY-19980 Human Interleukin 6,Peprotech,200–06 Human Interleukin

(7) Genotoxic formaldehyde and lipid aldehydes are sources of DNA damage in keratinocytesbioRxivJanuary 18, 2026Nicolas J. Blobel, Yibing Yao, Marian C. Okondo, Agata Smogorzewskaas described above and treated with indicated doses of MMC, paraformaldehyde (#15710, EMS), ML210 (HY-100003, MedChemExpress) or 4-hydroxynonenal (#32100, Cayman Chemical) on the following day. The media remained

(8) Glutaminase‐1 Mediated Glutaminolysis to Glutathione Synthesis Maintains Redox Homeostasis and Modulates Ferroptosis Sensitivity in Cancer CellsCell ProliferationNovember 1, 2025Changsen Bai, Jialei Hua, Donghua Meng, Yue Xu, Benfu Zhong, Miao Liu, Zhaosong Wang, Wei Zhou, Liming Liu, Hailong Wang, et al.(PC),1957/11/4,Aladdin,L130331 Phosphatidylglycerol (PG),1957/10/3,Aladdin,L130372 BPTES,314045‐39‐1,MCE,HY‐12683 ML‐210,1360705‐96‐9,MCE,HY‐100003 ED‐71,104121‐92‐8,MCE,HY‐A0020 CCK‐8,N/A,TargetMol,C0005 Reagents used in this study.

(9) Exploiting dysregulated iron homeostasis to eradicate persistent high-grade serous ovarian cancerCell Death DiscoverySeptember 25, 2025Carmelo Cerra, Madeleine R. C. Tancock, Niko Thio, Ada Koo, AnnRann Wong, Karla J. Cowley, Swati Varshney, Madelynne O. Willis, Kaylene J. Simpson, Australian Ovarian Cancer Study Group, et al.USA). The following drugs were purchased from MedChemExpress (Monmouth Junction, NJ, USA): ML-210 (#HY-100003), RSL3 (#HY-100218A), FIN56 (#HY-103087), N6F11 (#HY-162065), ABT-263 (#HY-10087), ABT-737 (#HY-50907),

(10) Macrophages and macrophage extracellular vesicles confer cancer ferroptosis resistance via PRDX6-mediated mitophagy inhibitionRedox BiolAugust 16, 2025Naisheng Zheng, Fuli Li, Qing Huang, Xian Huang, Tomasz Maj(Selleck, USA, #S8155), erastin (Selleck, USA, #S7242), FIN56 (MCE, USA, #HY103087), ML210 (MCE, USA, #HY100003), IKE (MCE, USA, #HY114481) or ferrostatin-1 (Selleck, USA, #S7243) to induce or inhibit ferroptosis,

(11) Lactylation of HDAC1 Confers Resistance to Ferroptosis in Colorectal CancerAdvanced ScienceJanuary 31, 2025Zhou Yang, Wei Su, Qinglin Zhang, Lili Niu, Baijie Feng, Yu Zhang, Feng Huang, Jiaxin He, Qinyao Zhou, Xin Zhou, et al.(HY‐13629), vemurafenib (HY‐12057), SAHA (HY‐10221), binimetinib (HY‐15202), cetuximab (HY‐P9905), ML210 (HY‐100003), FINO2 (HY‐129457), DFO (HY‐B0988), necrostatin‐1 (HY‐15760), Z‐VAD‐FMK (HY‐16658B), pyroxamide (HY‐13216),

(12) Selenium-SelK-GPX4 axis protects nucleus pulposus cells against mechanical overloading-induced ferroptosis and attenuates senescence of intervertebral discCellular and Molecular Life SciencesDecember 1, 2024Chunwang Jia, Ziqian Xiang, Pengfei Zhang, Long Liu, Xuetao Zhu, Ruixuan Yu, Zhicheng Liu, Shaoyi Wang, Kaiwen Liu, Zihao Wang, et al.(HY-110188, MCE, USA), 10 μM BAPTA-AM (HY-100545, MCE, USA), 5 μM Se-Met (HY-114245, MCE, USA), 10 μM ML210 (HY-100003, MCE, USA). At the end of the pressure application, the cells or the femoral head were placed in new

(13) Development of small-molecule probes that selectively kill cells induced to express mutant RASBioorganic & medicinal chemistry lettersFebruary 15, 2012Weïwer M, Bittker JA, Lewis TA, Shimada K, Yang WS, MacPherson L, Dandapani S, Palmer M, Stockwell BR, Schreiber SL, et al.

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ML-210 from MedChemExpress

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ML-210 from MedChemExpress

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