Description
A synthetic flavonol; reduces nicotine-induced cytotoxicity and ROS production in NRK-52E cells at 20 µM; inhibits the motility of U2OS, and the invasiveness of 143B, cells at 30 and 50 µM; reduces tumor growth in a 143B mouse xenograft model at 10 and 20 mg/kg; reduces the formation of pulmonary metastases in a 143B mouse model of metastasis at 20 mg/kg; reduces acetic acid-induced writhing in mice (ED50 = 55 mg/kg)