RV-1729 from MyBioSource.com

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RV-1729

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Description

RV-1729 is a potent, selective PI3Kdelta inhibitor with IC50 of 12nM, 2-fold selectivity for PI3Kdelta relative to PI3Kgamma and 16-fold over PI3Kalpha; inhibits PMA-induced peroxide production in U937 cells and phosphorylation of Akt