Description
MS7972 is a small molecules that blocks p53 and CREB binding protein (CBP) association; completely blocks CBP BRD/p53-AcK382 interactions at 50uM, results in loss of p53 phosphorylation at Ser15 as well as acetylation at Lys382; causes a dramatic decrease of the doxorubicin-induced p53 increase in U2OS cells