Description
LLP2A is a high-affinity, selective peptidomimetic ligand of alpha4beta1 integrin with IC50 of 2 pM; shows no binding affinity for alpha2beta1, alpha6beta1, alphaLbeta2 and alphaMbeta2 integrins; can be used to image alpha4beta1-expressing lymphomas with high sensitivity and specificity when conjugated to a near infrared fluorescent dye in a mouse xenograft model