Compound 401 from MyBioSource.com

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Compound 401

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Description

A synthetic inhibitor of DNA-PK also inhibits mTOR (IC50=5.3uM); no inhibition on p110alpha/p85alpha PI3K (>100uM); blocks the phosphorylation of S6 kinase 1 Thr389 and Akt Ser473 in COS7 cells