Gefitinib-based PROTAC 3 from MyBioSource.com

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Gefitinib-based PROTAC 3

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Description

Gefitinib-based PROTAC 3 is a VHL-recruiting PROTAC that induces the degradation of EGFR and EGFR mutants with DC50 of 11.7nM and 22.3nM for HCC827 cell (Exon 19 del) and H3255 cell (L858R)