S-Ruxolitinib from MyBioSource.com

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S-Ruxolitinib

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Description

Ruxolitinib (INCB018424) is the first potent selective JAK1/2 inhibitor to enter the clinic with IC50 of 3.3nM/2.8nM in cell-free assays >130-fold selectivity for JAK1/2 versus JAK3