Pifithrin-beta hydrobromide from MyBioSource.com

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Pifithrin-beta hydrobromide

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Description

A cyclic analog of Pifithrin-alpha and a small molecule inhibitor of p53; prevents dexamethasone-induced cell death in murine thymocytes with EC50 of 2.01uM, sensitizes p53-deficient tumors to radiotherapy and chemotherapy and increases apoptosis in cancer cells