Aprocitentan from MyBioSource.com

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Aprocitentan

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Description

Aprocitentan (ACT-132577) is the major and pharmacologically active metabolite of Macitentan. Aprocitentan is dual ETA/ETB antagonist with IC50s of 3.4nM and 987nM, and pA2 valus of 6.7 and 5.5, respectively