Description
A fluorescent copper complex with anticancer activity; localizes to mitochondria; ex/em = 455-495/535 nm, respectively; inhibits the growth of BxPC-3, AsPC-1, PANC-1, and WI38 pancreatic cancer cells (IC50s = 0.74, 0.41, 0.62, and 2.06 µM, respectively); induces lipid peroxidation and mitochondrial rupture and shrinkage in AsPC-1 cells; induces mitochondrial apoptosis and cytokine-cytokine receptor interaction dysfunction in the same cells; reduces tumor volume and intratumor apoptosis in an AsPC-1 mouse xenograft model at 1.5 and 3 mg/kg