Description
An isoflavone glycoside with diverse biological activities; inhibits oleic acid-induced lipid accumulation in HepG2 cells and stimulates glucose uptake in C2C12 mouse skeletal muscle myoblasts at 10 µM; inhibits compound 48/80- or histamine-induced scratching behavior in mice at 2 mg/kg; reduces serum levels of IgE in a mouse model of atopic dermatitis; increases serum levels of osteocalcin and ALP and restores mechanical bone hardness in an ovariectomized rat model of osteoporosis; decreases hepatic cholesterol and triglyceride levels, serum LDL and apolipoprotein B levels, and hepatic injury in a mouse model of fructose-induced liver injury at 80 and 160 mg/kg