Description
A steroidal saponin with diverse biological activities; inhibits UGT1A4 (IC50 = 10.5 µM); cytotoxic to K562 cells (IC50 = ~7.5 µM); improves neurological function and decreases neuronal damage in a rat model of spinal cord injury at 100 mg/kg; decreases serum levels of glucose, insulin, and triglycerides in diabetic db/db mice at 50 mg/kg; reduces serum MDA levels and stomach MPO activity in a mouse model of ethanol-induced gastric ulcers