Withanone from Cayman Chemical

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Cayman Chemical for
Withanone

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Description

A phytochemical with diverse biological activities; inhibits the protein-protein interaction between human ACE2 and the SARS-CoV-2 spike protein receptor-binding domain (IC50 = 0.33 ng/ml); protects against methoxyacetic acid-induced DNA damage, oxidative stress, and premature senescence in TIG-1 cells at 10 µg/ml; decreases brain levels of Aβ42, MDA, TNF-α, IL-1β, and IL-6, increases brain levels of acetylcholine, and improves cognitive function in a rat model of streptozotocin-induced sporadic Alzheimer’s disease from 5-20 mg/kg