Description
It is produced by the strain of Streptomyces sp. DO-114. Clecarmycin C has anti-gram-positive bacteria activity with MIC 0.04-0.33µg/mL. It also showed strong cytotoxicity, with IC50 of 11.5 mg/mL against HeLa S3 cells, which was 10-20 times stronger than adriamycin