Description
RQ-00311651 is a novel T-type Ca channel inhibitor' which plays a role in neuropathic and visceral pain. RQ-00311651 notably inhibited T currents when tested at holding potentials of -65 ∼ -60 mV' but not -80 mV' in the Cav3.1- or Cav3.2-expressing cells. RQ-00311651 also suppressed high K-induced Ca signaling in those cells