Description
WAY 213613 is a potent and non-substrate inhibitor of EAAT2 (GLT-1), displaying > 44-fold selectivity over EAAT1 and EAAT3 (IC50 = 85, 3787 and 5004 nM for EAAT2, EAAT3 and EAAT1, respectively). WAY 213613 exhibits no activity towards ionotropic and metabotropic glutamate receptors