Description
ML348, also known as CID 3238952 or SID 160654487, is a selective and reversible lysophospholipase 1 (LYPLA1) inhibitor (IC50 = 210 nM). It is 14-fold selective for LYPLA1 over LYPLA2 (IC50 = >3,000) and demonstrates little activity against a panel of more than 20 other serine hydrolases (IC50s = >10,000)