Description
S 32826 is an autotaxin inhibitor (IC50 = 9 nM) exhibiting similar inhibitory effects at all three autotaxin isoforms (α, β and γ). S 32826 displays no affinity for lysophosphatidic acid receptor 1 (LPA1) at concentrations up to 10 µM. It inhibits LPA release from adipocytes (IC50 = 90 nM)