Description
Rilmenidine hemifumarate, a centrally acting antihypertensive agent, is an I1-imidazoline binding site selective ligand and α2-adrenoceptor agonist. Rilmenidine targets the nonadrenergic imidazoline-binding site I1 receptor with a Ki value of 7.1 nM and demonstrates weaker affinity for the I2 receptor with a Ki value of 5.2 µM