Description
SC 57461A is a potent, selective and orally bioactive inhibitor of leukotriene A4 (LTA4) hydrolase without inhibitory effects on other enzymes of the arachidonic acid cascade including COX-1, COX-2, LTC4 synthase and 5-lipoxygenase. SC 57461A inhibits LTB4 production in whole blood (IC50 = 49 nM)