RBN-2397 from Cayman Chemical

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RBN-2397

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Description

A PARP7 inhibitor; stabilizes wild-type PARP7 levels, but not levels of the catalytically inactive mutant PARP7H532A, in COS-1 cells expressing wild-type or mutant PARP7, respectively, at 100 nM; decreases wild-type PARP7 catalytic activity in the same cells at 100 nM