Description
A triterpenoid; inhibits ACE (IC50 = 745 µM); inhibits HIV-1 protease (IC50 = 180 µM); reduces the proliferation of murine Lewis lung carcinoma cells but not murine Meth A sarcoma cells (EC50s = 17 and >20 µg/ml, respectively); inhibits LPS-induced NF-κB phosphorylation and production of TNF-α in RAW 264.7 cells and PBMCs isolated from patients with asthma at 20 µg/ml