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Protein Biochemistry
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JNK Inhibitor XVI
JNK Inhibitor XVI from Cayman Chemical
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Citations:
(3)
Supplier Page
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Cayman Chemical for
JNK Inhibitor XVI
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Description
A selective, irreversible JNK inhibitor (IC50s = 4.67, 18.7, and 0.98 nM for JNK1, 2, and 3, respectively); prevents phosphorylation of c-Jun in A375 and HeLa cells (EC50s = 338 and 486 nM, respectively)
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
JNK Inhibitor XVI
Company
Cayman Chemical
Price
$207.00
Supplier Page
View Company Product Page
Catalog Number
18096
Format
A crystalline solid
Research Area
Cancer, Cell Death, Cell Signaling, JNK Signaling
Molecular Weight
507.6
Quantity
25 mg
Purity
≥95%
Storage
-20
Formula
C29H29N7O2
Origin
CHN
Type
Inhibitors
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Cayman Chemical
Cayman Chemical Company 1180 East Ellsworth Road
Ann Arbor
,
Michigan
48108
United States
Phone
: (800) 364-9897
(734) 971-3640
Company Profile
Website:
http://www.caymanchem.com/
Citations (3)
(1)
Squamous-state excursions activate APOBEC3A in cancer
bioRxiv
May 28, 2026
Josefine Striepen, Alexandra Dananberg, Aušrinė Ruzgaitė, Alyssa Hurley, Eléonore Toufektchan, Ashley Nichols, Hannah Rosenberg, Cameron Cordero, Tony M. Mertz, Roshan Xavier Norman,
et al.
duration varying by experiment as specified in figure legends. JNK
inhibitor
(JNK-IN-8,
Cayman Chemical
,
18096
) was used at 10 μM. TAK1 inhibitor (
Takinib
,
MedChemExpress
,
HY-103490
) was used at 10 μM. ATM
inhibitor
(2)
Ubiquitination-activated TAB–TAK1–IKK–NF-κB axis modulates gene expression for cell survival in the lysosomal damage response
Elife
September 24, 2025
Akinori Endo, Chikage Takahashi, Naoko Ishibashi, Yasumasa Nishito, Koji Yamano, Keiji Tanaka, Yukiko Yoshida
HS-276 (10 µM,
Sigma-Aldrich
, SML-3629),
BX-795
(2 µM,
Abcam
,
ab142016
), and JNK-IN-8 (10 µM,
Cayman
,
18096
).
Transcriptome analysis
Total RNA from RPE-1 cells was prepared using the
Qiashredder
kit (
QIAGEN
,
(3)
Ubiquitination-activated TAB–TAK1–IKK–NF-κB axis modulates gene expression for cell survival in the lysosomal damage response
eLife
September 24, 2025
Akinori Endo, Chikage Takahashi, Naoko Ishibashi, Yasumasa Nishito, Koji Yamano, Keiji Tanaka, Yukiko Yoshida
HS-276 (10 µM,
Sigma-Aldrich
, SML-3629),
BX-795
(2 µM,
Abcam
,
ab142016
), and JNK-IN-8 (10 µM,
Cayman
,
18096
).
Transcriptome analysis
Total RNA from RPE-1 cells was prepared using the
Qiashredder
kit (
QIAGEN
,
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JNK Inhibitor XVI from Cayman Chemical
Supplier Page
View Company Product Page
$207.00
Product Specs
Company Info
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