Description
A triterpenoid sapogenin; inhibits the growth of HepG2, A549, MCF-7, and HCT116 cancer cells (IC50s = 63.20, 40.88, 61.96, and 92.53 µM, respectively); reduces tumor growth in an HCT116 mouse xenograft model at 30 mg/kg; inhibits HBV DNA replication in HepG 2.2.15 cells (IC50 = 148.15 µM); decreases the escape latency in the MWM in an APP/PS1 mouse model of Alzheimer’s disease at 50 mg/kg