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GSK503
GSK503 from Cayman Chemical
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Citations:
(2)
Supplier Page
Supplier Page from
Cayman Chemical for
GSK503
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Description
A selective inhibitor of EZH2 that prevents the methyltransferase activity of wild-type and mutant EZH2 with similar potency (apparent Ki = 3-27 nM); effective in vivo in mouse models of cancer
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
GSK503
Company
Cayman Chemical
Price
$106.00
Supplier Page
View Company Product Page
Catalog Number
18531
Format
A crystalline solid
Research Area
Cancer, Epigenetics, Transcription, & Translation, Histone Methylation, Metabolism, Writers
Molecular Weight
526.7
Quantity
5 mg
Purity
≥98%
Storage
-20
Formula
C31H38N6O2
Origin
USA
Type
Inhibitors
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Cayman Chemical
Cayman Chemical Company 1180 East Ellsworth Road
Ann Arbor
,
Michigan
48108
United States
Phone
: (800) 364-9897
(734) 971-3640
Company Profile
Website:
http://www.caymanchem.com/
Citations (2)
(1)
Dual EZH1/2 inhibition enhances DNMT inhibitor efficacy in colon cancer through targeting H3K27me1
bioRxiv
September 22, 2025
Alison A. Chomiak, Ashley K. Wiseman, Joel Hrit, Yanqing Liu, Stephanie Stransky, Simone Sidoli, Rochelle L. Tiedemann, Scott B. Rothbart
HY-157164
),
GSK126
(
Selleck Chemicals
S7061
),
GSK343
(
Selleck Chemicals
S7164
),
GSK503
(
Cayman Chemical
18531
),
MAK683
(
MedChemExpress
S8983), mevrometostat (MEV or PF-1497, Chemietek CT-PF0682),
MS177
(Selleck
(2)
Druggable epigenetic suppression of interferon-induced chemokine expression linked to MYCN amplification in neuroblastoma
Journal for immunotherapy of cancer
May 1, 2021
Seier JA, Reinhardt J, Saraf K, Ng SS, Layer JP, Corvino D, Althoff K, Giordano FA, Schramm A, Fischer M,
et al
.
CPI-1205 (Selleck Chemicals, #S8353), EED226 (
Selleck Chemicals
, #S8496),
GSK503
(
Cayman Chemical
, #
18531
) and
EPZ011989
(
MedChemExpress
, #
HY-16986
) were added to the culture media at a concentration of 3 µM
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GSK503 from Cayman Chemical
Supplier Page
View Company Product Page
$106.00
Product Specs
Company Info
Citations
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