K-Ras(G12C) Inhibitor 12 from Cayman Chemical

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K-Ras(G12C) Inhibitor 12

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Description

An allosteric inhibitor of oncogenic K-Ras(G12C); decreases viability and increases apoptosis in several lung cancer cell lines that contain G12C mutations (EC50 = 0.32 µM in H1792 cells)