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3-Nitropropionic Acid
3-Nitropropionic Acid from Cayman Chemical
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Citations:
(2)
Supplier Page
Supplier Page from
Cayman Chemical for
3-Nitropropionic Acid
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Description
An irreversible inhibitor of mitochondrial Complex II succinate dehydrogenase, resulting in energy depletion through disruption of the electron transport chain; used in animal models of Huntington’s disease and epilepsy
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
3-Nitropropionic Acid
Company
Cayman Chemical
Price
$525.00
Supplier Page
View Company Product Page
Catalog Number
14684
Format
A crystalline solid
Research Area
Cell Biology, Cell Health & Viability, Environmental Toxicology, Huntington’s Disease, Mitochondrial Biology, Mitochondrial Dysfunction, Neurodegenerative Disorders, Neuroscience, Neurotoxicity, Organ- & System-Specific Toxicity, Plant Biology, Seizure Disorders, Toxic Agents, Toxicology & Xenobiotic Metabolism, Toxins
Molecular Weight
119.1
Quantity
10 g
Purity
≥95%
Storage
-20
Formula
C3H5NO4
Origin
USA
Type
Inhibitors
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Cayman Chemical
Cayman Chemical Company 1180 East Ellsworth Road
Ann Arbor
,
Michigan
48108
United States
Phone
: (800) 364-9897
(734) 971-3640
Company Profile
Website:
http://www.caymanchem.com/
Citations (2)
(1)
Identification of Potential Therapeutic Agents for Type I Interferonopathy Using iPSC-Based Disease Modeling
Journal of Clinical Immunology
December 1, 2025
Bunki Natsumoto, Hirofumi Shoda, Motonori Tsuji, Makoto Otsu, Hideki Taniguchi, Kazuhiko Yamamoto, Keishi Fujio
inhibitors
(MTCIs), including MT-I
inhibitor
(
Rotenone
) (
13995
), MT-II
inhibitor
(
3-nitropropionic acid
) (
14684
), and MT-V
inhibitor
(
Oligomycin A
) (
19162
), were purchased from
Cayman Chemical
[17, 18]. MT-IV
inhibitor
(2)
Accumulation of succinate suppresses de novo purine synthesis through succinylation-mediated control of the mitochondrial folate cycle
Molecular Cell
November 20, 2025
Mushtaq A. Nengroo, Austin T. Klein, Heather S. Carr, Olivia Vidal-Cruchez, Umakant Sahu, Daniel J. McGrail, Nidhi Sahni, Niklas B. Thompson, Peter A. Faull, Peng Gao,
et al.
vials,Fischer,986548 Chloramphenicol,Sigma,C0378-5G
KOD Xtreme™ Hot Start DNA Polymerase
,
Millipore
,
71975-3
3-Nitropropionic Acid
,
Cayman
,
14684
Quick ligase,
NEB
,
M2200S
ethanol,Fischer,2701
Trypsin
,
Fisher
,25-052-CI
BbsI-HF
,
NEB
,
R3539S
BsmBI-v2
,
NEB
,
R0739S
syringe
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3-Nitropropionic Acid from Cayman Chemical
Supplier Page
View Company Product Page
$525.00
Product Specs
Company Info
Citations
Reviews
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