Pyr3 from Cayman Chemical

A selective TRPC3 inhibitor that prevents TRPC3-mediated Ca2+ influx (IC50 = 0.7 µM) without effect on other TRPC members; suppresses activation of NFAT (IC50 = 0.05 µM) and attenuates cardiac hypertrophy in mice at 0.1 mg/kg/day