Bofutrelvir from Cayman Chemical

An inhibitor of MPro (IC50 = 0.053 µM in a TR-FRET assay); reduces viral yield in the culture supernatant of SARS-CoV-2-infected Vero E6 cells (EC50 = 0.53 µM); reduces viral RNA copy numbers in the same model from 1.85-50 µM