SW155246 from Cayman Chemical

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SW155246

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Description

A DNMT1 inhibitor (IC50 = 1.2 µM); selective for human DNMT1 over murine DNMT3 (IC50 = 38 µM); inhibits HeLa and A549 tumor cell growth in a redox-independent manner (IC50s = 8-20 µM); inhibits genomic methylation in HeLa cells from 10 to 18.6 µM