Description
A quinolone antibiotic; active against E. coli, Pasturella, K. pneumoniae, A. aerogenes, Proteus, Salmonella, and Shigella (MBCs = 0.5-25 µg/ml); increases survival in mouse models of systemic K. pneumoniae, A. aerogenes, Proteus, or Salmonella infection (ED50s = 60, 35, 50, and 62 mg/kg, respectively)