Description
A P2X4 receptor antagonist (IC50s = 0.54 and 1.89 µM for the human and Xenopus receptors, respectively); selective for the human P2X4 receptor over the human P2X1, P2X2, P2X5, P2X3, and P2X7 receptors at 5 µM and over mouse and rat P2X4 receptors at 10 µM