Description
A macrocyclic lactone endectocide and a derivative of nemadectin; reduces fecal nematode egg counts by 98.4 and 99.8% in naturally infected calves at 0.2 and 0.3 mg/kg, respectively; reduces the worm burden of O. ostertagi and T. axei in the abomasum, and Cooperia species and N. helvetianus in the small intestine, of naturally infected calves at 0.2 and 0.3 mg/kg; potentiates GABA-gated currents in Xenopus oocytes expressing rat α1β2γ2 subunit-containing GABAA receptors (EC50 = 11.8 nM)