Description
A dual inhibitor of CK2 and ERK8 (IC50 = 0.5 µM for both); binds to Pim-1, HIPK2, and DYRK1A (Kis = 8.65, 15.25, and 11.9 µM, respectively) and inhibits greater than 50% of the activity of five kinases, including CK2, ERK8, and DYRK2, in a panel of 78 kinases at 10 µM; induces apoptosis in Jurkat cells at 10-50 µM