Cdk4 Inhibitor from Cayman Chemical

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Cdk4 Inhibitor

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Description

A cell-permeable, asymmetrical indolocarbazole that exhibits antiproliferative activity by selectively blocking cyclin D1/Cdk4 (IC50 = 0.8 µM); inhibits HCT116 and NCI-H460 tumor cell growth (IC50s 1 cell cycle arrest