Description
An irreversible urease inhibitor; inhibits the growth of struvite crystals in artificial urine; inhibits the growth of H. pylori in vitro (MICs = 200 and 400 mg/L for various isolates); chronic administration reduces urine urease activity, pH, and crystalluria and inhibits growth of bladder stones in dogs; decreases gastritis, gastric lesions, and bacterial infection rats in gerbils (2,500 ppm/animal) following, H. pylori infection