Description
An agonist of 5-HT7 receptors (Ki = 0.58 nM); selective for 5-HT7 over 5-HT1A and dopamine D2 receptors (Kis = 188 and 142 nM, respectively); induces relaxation of isolated guinea pig ileum precontracted by substance P (EC50 = 0.6 µM); stimulates neurite outgrowth in primary murine striatal and cortical neurons at 100 nM